RESPONDING TO COVID-19 SUB-VARIANTS

The Issue:

  • Since the initial report of the novel coronavirus in 2019, the virus has undergone numerous changes, resulting in over 1,000 subvariants and recombinant sub-lineages.
  • The emergence of the JN.1 sub-variant of the Omicron variant is part of the expected evolution of the virus, with genetic alterations in its genome leading to new classifications.
Source: COVID communication Network

Key Highlights:

  • Status :1, designated a Variant of Interest (VoI), triggers increased genomic sequencing and monitoring by health agencies.
  • Health Hazards : While JN.1 does not currently show evidence of causing severe disease or immune escape.
  • Vaccine Response : Current scientific evidence supports existing COVID-19 vaccines and hybrid immunity from natural infections against sub variants.
  • Impact : Globally, cases emerge in the US, Europe, Singapore, and China.
  • Impact on India: India reports JN.1 cases from Kerala and Goa.

Public Health Impact and Vaccines:

  • WHO states no evidence of additional public health risk from JN.1, but with the winter onset, it could heighten respiratory infections globally.
  • Assures existing vaccines continue to protect against severe illness and death caused by JN.1.
About Genome Sequencing

·   Process of determining the order of nucleotides in an organism’s DNA.

·   Involves breaking DNA into fragments, sequencing them, and assembling the sequence.

·   Enables identification of genes, variations, and understanding genetic codes.

·   Essential in various fields, including medicine, genetics, and evolutionary biology.