Ozempic Revolutionizes Diabetes and Obesity Management in India

Why in the news?

The popular diabetes drug Ozempic, now available in India as an oral tablet, is showing promising results in weight loss, diabetes control, and heart health but faces cost barriers.

Ozempic Revolutionizes Diabetes and Obesity Management in IndiaIntroduction:

  • Ozempic (semaglutide) has revolutionised the management of diabetes and obesity, gaining global popularity.
  • Initially approved in 2017 for Type 2 diabetes management, the drug’s injectable form, Wegovy, was later approved for chronic weight management.
  • The oral form, Rybelsus, launched in India in 2022, is offering new hope in weight loss and diabetes control.

How Ozempic Works:

  • Semaglutide mimics the GLP-1 hormone that helps regulate blood sugar by slowing digestion, reducing appetite, and increasing insulin release.
  • It helps in significant weight loss (10-15%) and provides additional benefits for heart and kidney health.
  • Doctors report positive results in managing diabetes and obesity, with Rybelsus being particularly effective when combined with a healthy lifestyle.

Challenges and Considerations:

  • While many patients experience noticeable weight loss, side effects like nausea, vomiting, and in rare cases, pancreatitis, may occur.
  • The drug is mainly prescribed to patients with diabetes and obesity who are at high cardiovascular risk.
  • However, its high cost (₹10,000 per month) and limited accessibility make it a barrier for many in India.
  • Despite these challenges, the drug has become a significant option in managing both diabetes and obesity, with ongoing studies exploring its potential for other health conditions.

About Ozempic Drug:

  • Purpose: Ozempic, a brand for the drug semaglutide, is FDA-approved for treating Type-2 diabetes by managing blood sugar levels.
  • Administration: Available in injectable and oral forms, it offers flexible options for patients.
  • Mechanism: Ozempic mimics GLP-1, a natural hormone that promotes insulin release and slows glucose release from the liver, helping regulate blood sugar.
  • Side Effect Concern: Some patients report “Ozempic face” as a side effect, characterised by facial ageing and skin sagging.

Sources Referred:

PIB, The Hindu, Indian Express, Hindustan Times