INDIA FACES RISING THREAT OF RESISTANT FUNGAL INFECTIONS
Why in the news?
The emergence of drug-resistant fungal infections, especially Trichophyton indotineae, is causing widespread treatment challenges in India, linked to steroid misuse and diagnostic delays.
source:researchgate
Emergence of Resistant Fungal Infections
- Rising Threat: Drug-resistant fungal infections, particularly Trichophyton indotineae, are becoming a significant health issue in India. This dermatophyte, linked to excessive use of topical steroids, is challenging to treat.
- Clinical Challenges:
- Persistent, treatment-resistant rashes are often misdiagnosed as eczema, delaying correct treatment.
- Accurate diagnosis requires both clinical examination and advanced laboratory tests, including fungal cultures and molecular diagnostics.
- Misdiagnosis and delayed treatment can lead to infection spread and increased community risk.
Treatment Difficulties
- Resistance Issues:
- Trichophyton indotineae, identified in 2019, shows resistance to common antifungals like terbinafine and itraconazole.
- Suboptimal drug quality and misuse of steroid creams contribute to resistance and treatment complications.
- Treatment Options:
- Alternatives like itraconazole are necessary but come with side effects such as gastrointestinal issues and liver toxicity.
- Comprehensive skin care, including hydration and barrier creams, is essential to support treatment.
WHO’s Fungal Priority Pathogen List (FPPL):
Overview:
Aim:
Categories: Critical Priority Group:
High Priority Group:
Medium Priority Group:
About Types of Fungal Diseases: Common Infections:
Geographic-Based Infections:
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