• UGI USER
  • Apr 23, 2024
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“IISC RESEARCH OFFERS NOVEL APPROACH FOR CANCER VACCINE DEVELOPMENT.”

Why in the news?

“IISc develops synthetic compounds to target cancer cells, utilising serum albumin for efficient delivery, promising advancements in vaccine development.”

source:midine

About the IISc Breakthrough in Cancer Vaccine Development:

  • Indian Institute of Science (IISc) researchers develop a synthetic compound (antigen) to target cancer cells effectively.
  • The compound is designed to bind to a protein in the blood and travel to the lymph nodes, stimulating antibody production against cancer cells.
  • The IISc team utilises serum albumin, a natural protein abundant in blood plasma, as the carrier for the compound.
  • Unlike previous attempts with artificial carriers, serum albumin proves efficient in delivering the antigen to the lymph nodes, enhancing immune response without side effects.
What is an antigen?

●   Antigen: Marker recognizable by the immune system, like proteins or sugars.

●   Found on cells, viruses, bacteria, allergens, and tumour cells.

●   Categorised into exogenous, endogenous, autoantigens, and tumour antigens based on origin.

●   Self-antigens: Recognized as ‘self’, non-self as intruders.

About Indian Institute of Science (IISc) :

●   Indian Institute of Science (IISc) is a premier public research university.

●   Located in Bengaluru, Karnataka, India.

●   Established in 1909 with support from Jamsetji Tata.

●   Renowned for advanced scientific and technological research.

●   Considered one of India’s finest educational institutions.

source:

https://www.thehindu.com/news/national/karnataka/this-iisc-research-provides-a-new-direction-to-develop-vaccine-candidates-for-cancer/article68094505.ece#:~:text=Researchers%20at%20the%20Indian%20Institute,of%20antibodies%20against%20cancer%20cells.