• UGI USER
  • Jan 29, 2024
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GENOMIC REVOLUTION IN CANCER CARE

Why in the News?

  • Recent UK research with 13,800 cancer patients showed genomic integration with clinical data can identify new cancer targets, guiding treatment strategies and highlighting inherited risks.
  • NHS explores genomic medicine integration in cancer care, some trusts use preemptive sequencing.
Source: ToI

Insights from study:

  • Whole-Genome Sequencing: Central to the transformation of cancer care is whole-genome sequencing, enabling the comprehensive analysis of an individual’s DNA in a single test.
  • Cancer Burden: With cancer becoming a significant global health concern, initiatives like the Cancer Genome Atlas aim to understand the molecular basis of cancer, leading to the development of precision oncology therapies.
  • Precision Oncology: Molecular tests determine eligibility for precision oncology therapies, with genomic medicine showing potential to revolutionize cancer treatment by customizing therapies based on genomic data.
Key Terms

Genome Sequencing:

Genome sequencing is the process of determining the complete DNA sequence of an organism’s genome. It involves reading the order of nucleotides (A, T, C, and G) in DNA strands, providing insights into genetic variations and potential disease risks.

Oncology

Oncology is the branch of medicine focused on the diagnosis, treatment, and prevention of cancer. Oncologists study the causes and progression of cancer, develop treatment plans such as surgery, chemotherapy, and radiation therapy, and work towards improving patient outcomes.